The Malmberg Lab at the University of Wyoming (UW)/Wyoming State Veterinary Laboratory (WSVL) is seeking candidates for a postdoctoral research associate to develop and implement real-time quaking-induced conversion (RT-QuIC) for detection of chronic wasting disease (CWD). RT-QuIC will be applied to multiple current and future research projects in collaboration with the Wyoming Game and Fish Department (WGFD), Wyoming Cooperative Fish & Wildlife Research Unit, and the Wildlife Genomics & Disease Ecology Laboratory to better understand CWD dynamics and inform management of free-ranging cervids. In addition to CWD project responsibilities the selected candidate will be expected to take a leadership role in the Malmberg lab, which includes but is not limited to mentorship of graduate and undergraduate students, involvement in other lab research projects, coordination of lab meetings, and leadership on lab-generated publications.
Studies have demonstrated chronic wasting disease (CWD) as a direct cause of population declines in Wyoming mule deer (Odocoileus hemionus) and white-tailed deer (Odocoileus virginianus), where CWD prevalence in some hunt areas exceeds 50%. Currently CWD prevalence in elk (Cervus canadensis) is notably lower than in sympatric deer; however, there is evidence that population-level impacts of CWD on elk are likely in absence of improved strategies for disease control. While much progress has been made toward understanding CWD pathogenesis and transmission, advancements are limited by the low sensitivity of conventional prion detection techniques during the early (pre-clinical) phase of infection. RT-QuIC involves amplification of low levels of prions to detectable levels, allowing for sensitive, early detection, thereby supporting both natural field studies of prion diseases as well as controlled clinical investigations. This assay can be modified to support a variety of research objectives.
The Malmberg Lab (www.malmberglab.org) consists of a small but dynamic team of students and scientists in Department of Veterinary Sciences at the University of Wyoming/Wyoming State Veterinary Laboratory. Dr. Malmberg is a board-certified anatomic pathologist with expertise in pathogenesis and evolution of infectious diseases of wildlife. The selected candidate will have access to state-of-the-art equipment at the Wyoming State Veterinary Laboratory and opportunities to participate in interdisciplinary programs and collaborations at UW. Opportunities to gain teaching experience are available if desired. This is a 2-year position with competitive salary and benefits that may be extended contingent upon performance and extramural funding. We recognize the scientific benefits of diverse collaborations with people from varied backgrounds, and we encourage applicants from underrepresented groups to apply.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
Based on protocols and technical expertise provided by experienced external collaborators, the successful candidate will be expected to develop and implement RT-QuIC and contribute to multiple current and future CWD research projects. Responsibilities include designing and performing controlled assays and experiments, analyzing data, and communicating results to diverse stakeholders including local, state, and federal agencies. Presentation of research findings at national or international meetings is expected. The selected candidate will also be responsible for writing of manuscripts and proposals for extramural funding. Additional essential duties include supporting and mentoring graduate and undergraduate students on other projects, including in vitro and genomic characterization of Mycoplasma bovis in pronghorn (Antilocapra americana) and statewide assessment of CWD genetics and population genomics in elk (Cervus canadensis).
A Doctoral Degree is required for this position, however, consideration will be given to applicants that are currently pursuing their Doctoral Degree and will complete the degree prior to starting work.
-Ph.D. in a relevant discipline (will consider All But Defended applicants (ABD))
-Strong statistical and analytical skills
-Ability to work independently
-Evidence of strong written and oral communication skills
-Valid driver's license with a motor vehicle record (MVR) that is compliant with the University Official Vehicle Policy found at: https://www.uwyo.edu/risk/_files/docs/offical-vehicle-policy.pdf
Competitive candidates will have one or more of the following:
-Experience working with prions in a research laboratory setting
-Molecular laboratory and bioinformatic analysis skills
-Experience with R, ArcGIS, Bayesian phylogenetics and phylogeography and/or other spatial analysis tools
-Ability to design, interpret and communicate applied studies in disease ecology, wildlife management, or conservation science
-Demonstrated ability to work collaboratively and professionally with diverse stakeholders
-Demonstrated communication of scientific findings through publications and presentations
Complete the online application and upload a single PDF file containing a cover letter, CV, academic transcript, and contact information for four references. Review of applications will continue until a suitable applicant is identified.
UW is an Affirmative Action/Equal Opportunity Educator and Employer. We are committed to a multicultural environment and strongly encourage applications from women, minorities, veterans and persons with disabilities.
In compliance with the ADA Amendments Act (ADAAA), if you have a disability and would like to request an accommodation to apply for a position, please call 307-766-2377 or email firstname.lastname@example.org.
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